联系我们

  • 兰州市天水南路222号贵勤楼319室
  • 730000
  • 0931-8912168
  • 0931-8912440
  • yzb@lzu.edu.cn
  • http://yz.lzu.edu.cn
  • 厍学功

    【来源:兰州大学研究生处 | 发布日期:2016-11-16 】     【选择字号:

    厍学功,理学博士,兰州大学二级教授、博士生导师,国家杰出青年基金获得者。
        主要从事不对称催化反应、天然产物的不对称全合成及相关方法学研究。围绕天然产物全合成中的核心科学问题,设计、发展了多样性、去对称化、多组分(串联)反应等合成策略,建立了一些基于天然产物合成的骨架构筑新方法,从而简捷、高效地完成了30 多个具有抗HIV、抗癌、杀菌等活性的天然产物全合成,其中 20多例为首次全合成报道。
        曾荣获2000甘肃省高校科技进步奖一等奖;2001甘肃省科技进步二等奖2004甘肃省高校科技进步奖一等奖。2005甘肃省科技进步奖二等奖2005年首届兰州市青年科技奖 2007甘肃省自然科学二等奖2007“Thieme Chemistry Journal Award” 2009甘肃省科技领军人才2010年第四届药明康德生命化学研究奖,2010Asian Core Program Lectureship Award2013年获甘肃省优秀专家2013Asian Core Program Lectureship Award
        先后主持或完成国家杰出青年基金 1项、国家自然科学基金5项、教育部科学技术研究重点项目1项、教育部高等学校博士点专项基金2项,参加科技部973项目1项和国家自然科学基金重点项目1项。在J. Am. Chem, Soc., Angew. Chem .Int. Ed., J. Org. Chem., Org. Lett.等国际著名学术期刊上发表论文一百二十余篇。
         代表性论文:
    1.  Ruoming Mei, Dengyu Xu, Haitao Hu, Dengpeng Song, Hao Zhang, Donghui Ma, Xingang Xie, and Xuegong She  Biomimetic Total Syntheses of (+)-Dihydrolyfoline and (?)-5-epi-Dihydrolyfoline
    Org. Lett., 2015, 17 (9), 2230–2233
    2. Changgui Zhao.; Xingang Xie,.; Shuangshuang Duan; Huilin Li.; Ran Fang,.Xuegong She* , Gold-Catalyzed 1,2-Acyloxy Migration/Intramolecular[3+2] 1,3-Dipolar Cycloaddtion Cascade Reaction: An Efficient Strategy for Syntheses of Medium-Sized-Ring Ethers and Amines.
      Angew. Chem. Int. Ed. 2014, 53, 10789-10793.
    3
    Shiyan Xu, Jixiang Gu, Huilin Li, Donghui Ma, Xingang Xie and Xuegong She*, Enantioselective Total Synthesis of (-)-Walsucochin B,
    Org. Lett., 2014, 16, 1996-1999.
    4. Huilin Li, Yuanyuan Zhang, Xingang Xie, Haicheng Ma, Changgui Zhao, Gaoyuan Zhao and Xuegong She*,  Bioinspired Total Synthesis of Gymnothelignan N,
    Org. Lett., 2014, 16, 4440-4443.
    5. Jing Qi, Xingang Xie, Runfeng Han, Donghui Ma, Juan Yang, and Xuegong She*,N-Heterocyclic Carbene (NHC)-Catalyzed/Lewis Acid Mediated Conjugate Umpolung of Alkynyl Aldehydes for the Synthesis of Butenolides: A Formal [3+2] Annulation
    Chemistry-A European Journal, 2013, 19, 4146-4150 
    6. Peng Jing, Zhen Yang, Changgui Zhao, Huaiji Zheng, Bowen Fang, Xingang Xie, and Xuegong She*  Total Synthesis of (±)-Kopsihainanine A
    Chem. Eur. J. 2012, 18, 6729 – 6732.
    7. Changgui Zhao, Huaiji Zheng, Peng Jing, Bowen Fang, Xingang Xie, and Xuegong She*, Tandem Oxidative Dearomatization/Intramolecular Diels-Alder Reaction for Construction of the Tricyclic Core of Palhinine A
    Org. Lett., 2012, 14, 2293-2295.
    8. Synthesis of the Tetracyclic Core (ABCE Rings) of Daphenylline
    Bowen Fang, Huaiji Zheng, Changgui Zhao, Peng Jing, Huilin Li, Xingang Xie, and Xuegong She*   J. Org. Chem. 2012, 77, 8367
    ?8373.
    9. Jiyue Zheng, Xingang Xie, Changgui Zhao, Yongping He,Huaiji Zheng, Zhen Yang, Xuegong She*  Total Synthesis of (-)-Przewalskin B
    Org. Lett., 2011, 13.173-175
    10.. Qipu Dai, Xingang Xie, Shiyan Xu, Donghui Ma, Shibing Tang, Xuegong She*  Total Syntheses of Tardioxopiperazine A, Isoechinulin A, and Variecolorin C
    Org. Lett., 2011, 13 (9), pp 2302–2305

    11. Ling Zhang, Xingang Xie, Jian Liu, Jing Qi, Donghui Ma, and Xuegong She*
    Concise Total Synthesis of (±)-Dasyscyphin D
    Org. Lett., 2011, 13 (11), pp 2956–2958
    12. .Zhen Yang, Bingbin Zhang, Gaoyuan Zhao, Juan Yang, Xingang Xie, and Xuegong She*  Concise Formal Synthesis of (+)-Neopeltolide
    Org. Lett., 2011, 13 (21),  5916–5919

    13. Huaiji Zheng, Xing Huo, Changgui Zhao, Peng Jing, Juan Yang, Bowen Fang, and Xuegong She*
    Au-Catalyzed Piperidine Synthesis via Tandem Acyloxy Migration/Intramolecular [3 + 2] Cycloaddition of Enynyl Esters,  Org. Lett., 2011, 13 (21), 6448–6451
    14.   Huaiji Zheng, Jiyue Zheng, Binxun Yu, Qiang Chen, Xiaolei Wang, Yongping He, Zhen Yang and Xuegong She*      Pt-Catalyzed Tandem 1,2-Acyloxy Migration/Intramolecular[3 2] Cyclaoaddtion of Enynyl Esters
       J. Am. Chem. Soc. 2010, 132 ,1788–1789.
    15,    Qiaoling Wang  qinggang huang  Xuegong She* and Xinfu Pan*Total Synthesis of (+)-Machaeriol D with a key Regio-and Stereoselective S N 2’ Reaction  Angew. Chem .Int. Ed., 2006. 45. 3651-3653
     

    版权所有 兰州大学研究生院