联系我们

  • 兰州市天水南路222号学生活动中心702室
  • 730000
  • 0931-8912168
  • 0931-8912440
  • yzb@lzu.edu.cn
  • http://yz.lzu.edu.cn
  • 涂永强

    【来源:研招办 | 发布日期:2016-11-15 】     【选择字号:

    涂永强,男,中国科学院院士,长江学者特聘教授,英国皇家化学会会员。195810月生于贵州遵义县,198219851989年在兰州大学化学系有机化学专业分别获得学士、硕士和博士学位; 1993-1995年在澳大利亚昆士兰大学作博士后研究员,1995年回国后在兰州大学任教授、博导, 2005年受聘教育部长江学者特聘教授”, 2009年当选中国科学院院士。曾任功能有机分子化学国家重点实验室主任、教育部科技委委员。2012年应邀担任英国皇家化学会杂志Chem. Comm. 副主编。曾获中国化学会青年化学奖,国家教委科技进步二等奖,香港求是基金会杰出青年学者奖,甘肃省科技进步一等奖,美国礼来公司"礼来科研成就奖"及甘肃省自然科学一等奖。2012年被授予全国优秀科技工作者称号。目前,主要从事具有生物活性天然产物的全合成、合成方法学等领域的研究,在国际知名学术刊物发表科研论文二百余篇。
        近期研究兴趣主要包括:
    1. 具有高生物活性的复杂天然产物的全合成;
    2. 新颖的1,2-重排串联反应及其在有机合成中的应用;
    3. 新颖的C-H键活化、C-CC-X)键连接反应研究。

    代表性论文:
    1. Tandem C–H oxidation/cyclization/rearrangement and its application to asymmetric syntheses of (?)-brussonol and (?)-przewalskine E
    Zhi-Wei Jiao, Yong-Qiang Tu,* Qing Zhang, Wen-Xing Liu, Shu-Yu Zhang, Shao-Hua Wang, Fu-Min Zhang, Sen Jiang
    Nature Commun. 2015, DOI: 10.1038 /ncomms8332
    2. Organocatalytic Asymmetric Tandem Nazarov Cyclization/Semipinacol Rearrangement: Rapid Construction of Chiral Spiro[4.4]nonane-1,6-diones
    Bin-Miao Yang, Pei-Jun Cai, Yong-Qiang Tu,* Zhi-Xiang Yu, Zhi-Min Chen, Shuang-Hu Wang, Shao-Hua Wang, Fu-Min Zhang
    J. Am. Chem. Soc. 2015, 137, 8344–8347.
    3. Divergent and Efficient Syntheses of the Lycopodium Alkaloids (?)-Lycojaponicumin C, (?)-8-Deoxyserratinine, (+)-Fawcettimine, and (+)-Fawcettidine
    Si-Hua Hou, Yong-Qiang Tu, Lin Liu, Fu-Min Zhang, Shao-Hua Wang, Xiao-Ming Zhang
    Angew. Chem. Int. Ed. 2013, 52, 11373-11376.
    4. Total Synthesis of the Nominal Didemnaketal A
    Fu-Min Zhang, Lei Peng, Hui Li, Ai-Jun Ma, Jin-Bao Peng, Jing-Jing Guo, Dengtao Yang, Si-Hua Hou, Yong-Qiang Tu,* William Kitching
    Angew. Chem. Int. Ed. 2012, 51, 10846–10850.
    5. Organocatalytic Asymmetric Direct Sp3 α-C–H Functionalization of Ethers: A Highly Efficient Approach to Chiral Spiroethers
    Zhi-Wei Jiao, Shu-Yu Zhang, Chuan He, Yong-Qiang Tu,* Shao-Hua Wang, Fu-Min Zhang, Yong-Qiang Zhang, Hui Li
    Angew. Chem. Int. Ed. 2012, 51, 8811–8815.
    6. Semipinacol Rearrangement in Natural Product Synthesis
    Zhen-Lei Song, Chun-An Fan, Yong-Qiang Tu*
    Chem. Rev. 2011, 111, 7523–7556.
    7. Stereoselective Construction of Quaternary Carbon Stereocenters via a Semipinacol Rearrangement Strategy
    Baomin Wang, Yong-Qiang Tu*
    Acc. Chem. Res. 2011, 44, 1207–1222.
    8. Direct Sp3 a-C–H activation and functionalization of alcohol and ether
    Shu-Yu Zhang, Fu-Min Zhang, Yong-Qiang Tu*
    Chem. Soc. Rev. 2011, 40, 1937–1949.
    9. Total Synthesis of (±)-Alopecuridine and Its Biomimetic Transformation into (±)-Sieboldine A
    Xiao-Ming Zhang, Yong-Qiang Tu,* Fu-Min Zhang, Hui Shao, Xing Meng
    Angew. Chem. Int. Ed. 2011, 50, 3916–3919.
    10. Organocatalytic Asymmetric Halogenation/Semipinacol Rearrangement: Highly Efficient Synthesis of Chiral α-Oxa-Quaternary β-Haloketones
    Zhi-Min Chen, Qing-Wei Zhang, Zhi-Hua Chen, Hui Li, Yong-Qiang Tu,* Fu-Min Zhang, Jin-Miao Tian
    J. Am. Chem. Soc. 2011, 133, 8818–8821
    11. Organocatalytic Asymmetric Vinylogous α-Ketol Rearrangement: Enantioselective Construction of Chiral All-Carbon Quaternary Stereocenters in Spirocyclic Diketones via Semipinacol-Type 1,2-Carbon Migration
    En Zhang, Chun-An Fan, Yong-Qiang Tu,* Fu-Min Zhang, Yan-Lin Song
    J. Am. Chem. Soc. 2009, 131, 14626–14627.
    12. Br?nsted Acid Catalyzed Enantioselective Semipinacol Rearrangement for the Synthesis of Chiral Spiroethers
    Qing-Wei Zhang, Chun-An Fan, Hai-Jun Zhang, Yong-Qiang Tu,* Yu-Ming Zhao, Peiming Gu
    Angew. Chem. Int. Ed. 2009, 48, 8572–8574.
    13. Iron-Catalyzed C(sp3)-C(sp3) Bond Formation via sp3 C-H Functionalization: A Cross-Coupling Reaction of Alcohols with Alkenes
    Shu-Yu Zhang, Yong-Qiang Tu,* Chun-An Fan, Fu-Min Zhang, Lei Shi
    Angew. Chem. Int. Ed. 2009, 48, 8761–8765.
    14. A Reaction for sp3-sp3 C-C Bond Formation via Cooperation of Lewis Acid- Promoted / Rh-Catalyzed C-H Bond Activation
    Lei Shi, Yong-Qiang Tu,* Min Wang, Fu-Min Zhang, Chun-An Fan, Yu-Ming Zhao, Wu-Jiong Xia
    J. Am. Chem. Soc., 2005, 127, 10836–10837.
    15. A Novel Tandem Semipinacol Rearrangement/Alkylation of a-Epoxy Alcohols: Efficient and Stereoselective Approach to Multifunctional 1,3-Diols
    Xiang-Dong Hu, Chun-An Fan, Fu-Min Zhang, Yong-Qiang Tu*
    Angew. Chem. Int. Ed. 2004, 43, 1702–1705.
    16. Samarium-Catalyzed Tandem Semipinacol Rearrangement/Tishchenko Reaction of a-Hydroxy Epoxides: A Novel Approach to Highly Stereoselective Construction of 2-Quaternary 1,3-Diol Units.
    Chun-An Fan, Bao-Min Wang, Yong-Qiang Tu,* Zhen-Lei Song
    Angew. Chem. Int. Ed. 2001, 40, 3877–3880.

     

    版权所有 兰州大学研究生院